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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '562ebd441866d7bf6adfca0f12e9f4dc7f0f16ec42e1e2f93f77acdf016a65ec' 
  AND token = 'Vfx+bXQ+U6emA77sC/tOnYWwcKHK1pce6Fjzj/WFd/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}