SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3c59074e7589f2f23de52d0be28e58e880bd9bb9943811b5b64af3da01da0d' 
  AND token = 'vf+0M13ga2WO+s5VJpGsknbCyLVrd6nXTzDqhp5owPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}