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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c62f1ebc65813a7cbe375d46eeaa6f0ed4f3c0461426e2ce86f3ac8074e0a2' 
  AND token = 'Zo4YCUIS+0e2iQ2Pivy+jppvyaGS7BoWvEQQK8MniuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}