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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8703fbc25f5a0ae9f86d405ba6a50b2245c36d12b7e5a942dc6029d2267c85a9' 
  AND token = 'A27BNY0ZmR6VNsZnMbQOBec1xaM3GYSLKm6iSf7Dnek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}