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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2133d6fdd050c167dc1c506ba393a12e6d7ab7631999c9d0d7603c9e463060e6' 
  AND token = 'WGH1dT8sEzpU7B/Ai8ulmpZkeZL4gkEb8xghHmKqbyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}