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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca95c9891a119e0991dcd17831f8a8da5a49d1da6d5419d3327e02d2e94d73d2' 
  AND token = 'qpav+wY8zENmkaGnQl3DVxSlAgQG8Mw2CL5Fzfn4EXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}