SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dfa6c3376aa6b8328dcaa5b3a6eb74f8c25c71ee4fd4d1013f02c39e704a0ec' 
  AND token = 'FOsanhj5/JVaLyNwSxriKPO1BgKFlII3/AtcshAr0+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}