SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d0aa92cbd359b55e502e2540becc1a933c406e1ff0dc78d9216868538f60f4' 
  AND token = 'Cr7c9DTXmC/6uBP4oisDK/ukvvLmWmELDKzfZIIZjQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}