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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e014a46172003b17e6bee674f4d6c51840a8ff944039709f4369d5ab97e4c06' 
  AND token = '25Af2MGmTyG1kMwowOMZv6g7L6+X69EzBFkvmxPlC+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}