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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11d514e0403510d5e7c85fde87f28a80cf3ef304a982d193cf94be8aea586277' 
  AND token = 'tHcRSw0c5e/ho6mbDd+fVoRVHx1CMCwVO4wYydQH8h4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}