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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eefbc918c0853db2d8200308b8c655d1f1161a0b0ad83cd6351a52a9361c1b3' 
  AND token = 'dCMBmkXS3ckEAIPWZPgIRfW0IKhjBA0QnOLGVq6Usf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}