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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50ab25029fe5600803ae33b4f41124f07baa7bebf72ee39d9973088d5a0b369' 
  AND token = 'pFo3mpayD+TuIFoaajUZOSuwGf5ITwaXRkQcqKYP9r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}