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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6c5d3e562ab944482cbf37a9a05391806133086d488765cec66b77404de3a30' 
  AND token = 'sKJb2u6LLKKPy1kNDVgwQSKlK/a1f1FjuOp4ebR8qTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}