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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bffbe76c921658873790a753e68783e3e2c4cae78c3f1a401376ab3068c770c6' 
  AND token = '+VNFR+7XfzVazCN6PT8VdbPfvDoMc3vY+LtzwanW3PA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}