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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4299d6cfc2636d9bc8a1b4b7a551f3221042968f2a36d0dea6e2be076635c6fc' 
  AND token = 'aJB89+3pw/wU3hE5MoFjFguWsjmw1iOrrMk7wEWxxRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}