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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea380d781e8a44a90cdacc8bc84d7ee4574387cae638be22d0c172a77c8f18fd' 
  AND token = 'jZ3k1AZrMKqKYL4kpDX1R2IZ6oN0YRamuw8swpZeUYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}