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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022417a33d436b78f04f3b14120b85e59fb14200f7400eb86b5b864f7e6710f5' 
  AND token = 'kqRoWuD53Z45bo+3RThXya1vaHHe1kuELI2OXWqgxcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}