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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf1c92eea55c3f2282a76d5ab79c5ee3c295569bffcadfd98a1e67355539c3a6' 
  AND token = '5R2rsdSg9Ffa6prBpN2ZeUlgRXztWU1CI+I73n28tfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}