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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3489d3dd225dadb2d40ed86f95be9667b65400b03c2b7653c6ba5f65f555cf02' 
  AND token = 'v780lhOWg3J0NLYbaBgfdtdDKHI3xJOaoF1oCfE/wjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}