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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16bddc35b67be1358c8243c0632673080c8375c63c34360964c6f6112cbc0a8' 
  AND token = 'jH7KsbL95MlpwOTAPtSdEh2zjDLy3OI/DIDWWN09/N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}