SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '742366ceeab1e11701a14979795c8d916f0544042fce3f7a9de6c89abc1e80d6' 
  AND token = 'f8aOxV2o733cCAPZajoPLdp1m2HI7l/BedbJNXqzvkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}