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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6686dcd7bac25cc638a00ebde2b15ae52cd5f8b9002afa33f41eba8e90bd4f' 
  AND token = 'fNH/YD5TewwMiMflv2YL41g8eqhlT4XKoiz8nxaa3F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}