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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb94708c3233de972b8e8e5bdb2151b50495767c6c0e18f95e91a7c47f603a4' 
  AND token = 'QLkWKnYvFMBL85NB8fBaYYqc3E6P2rRDaD9PjPOrFzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}