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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80f5da743ab27b26b55639d275d87d0ce5be0f62e37d0f0144aeb740e94a228' 
  AND token = 'c2Va0Yy4OPpv63b5aBCn4H6nxk4V8c0Zvx8r383Elzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}