SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '553848ccdbbbe928d0e52bb2b2d7bfda37703c039dff47d685767dd24438aa2d' 
  AND token = 'bcUD0W53peY/T30thREemrDgSQtCdgKdxjzDFNcM33Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}