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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '765d296a3185c028d652db67856a945a441a1c4ac41669cf50f8387a8387d946' 
  AND token = '9olOWnHL1c9cg8csa0jdhldiTG+JtGsOY098rG6IQDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}