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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a8f90ed5017c7095066765b405a77ba04a635cace3d802f71cdd1799c4c657' 
  AND token = 'LYB1Rxyp1SzAtugBfz20/0PRVL4cF9kFdX9gstiZuEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}