SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b42999739c51615c41a97e2a59877b72a3997edc60a8ea721f634313ea570e2' 
  AND token = '8xmicVi5TgpqHhl+t+kdLMwvtI8GIHumLn1blxTgNnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}