SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d531a862183f18c06afd11f10fc657235b475e6546d5cc4bb814d59851caccf' 
  AND token = 'rZU6/X+lmDcRmG94CmYtGAo5ZVRuOVhpxP0IMRuw+14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}