SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e8b4a30df22942953987a1f748750693d6aeb0540a15a8e9ec16db78cc8e13d' 
  AND token = 'mV4WZqaPPb8TjiIF+MiIC7w9USB1x6tGFimEov6RIk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}