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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3880ac0f5b3902acb396e4a382a9b6dcb4b49714c3b2312f644d7f467df990d4' 
  AND token = '6A+EX6tjwAVM8PM8m80127SrLzGdl8VkA0VdM6z+cNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}