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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '383a1d03f102dc2f9464eae49946a3aad8b800ab9001725fb1e08d0c66c07f9c' 
  AND token = 'XXI7XXzyzoqbQN+Zgc2LnxL+hODBucDxIn+4sZLJcg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}