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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295c09149c859585a5a164f6ad9567fc77b72080f2673933ac673e8a6b1b8cae' 
  AND token = '1XeV25E4Z1sXArMbAK3s3pjYxtuGFG2ijNERuDorHVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}