SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e74793db93c8f45e89342fa95cfff0e5cb96c81e1dc609756a4d844b431ee3b' 
  AND token = 'LPK9VTlCHls7AM6jXgVAoUCXzdcG/9FCI9KRohzHrlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}