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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ac0d2715b31efb8983a66e2c650ce2387a2abd08640a3711ef77e48dafebcc' 
  AND token = 'bwIleis4YDTXG/nl1E4g137IKvsO7ccGj/uqBbsGrCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}