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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e8a66d868a91d92683b4bddfdf2e18c63bdaccee302392dd69484a5630b43c' 
  AND token = 'IFcchIKRvNzfZHJsOOPGvZ8uEe7Co4L4BQIqdz2hyjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}