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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6705f2213bf5764d3f10a986a52150ef9ed6d7f6c0b84c491dedfe71fd2c649' 
  AND token = 't4hmGrd51D+CMxYmprDQRlxuWMy6bIuRfn26pa0zS10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}