SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f81f2681c18d03853167e8ff27dce6eff52e02fd713273a85f4f7601d02a78d' 
  AND token = 'HY8qN6l0cn+UL6MpCjqXvcsw7+bfefxn2apexbPXAjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}