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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a00f6c53cc39ff207019db201e5df45a0a16ef3cd27b97736b29b8aae90a6aa' 
  AND token = 'SSCCui7nPa02KrQO6eY4bEIY/EmkO9y7UXLH18Y8t7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}