SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e2f204b2f58d82b83a83dca626f3e24b3697afbdde00d39dab03812f1164ff' 
  AND token = '5PbouFqiTsEdBWJvo28W3KZQgLzz28Qy29dqyihVF/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}