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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc3d71c145ae860f39537cea95a6d2e768a705e48723911d5622b2f69a0a7a3' 
  AND token = 'unCETOZqIFWqY/BKu+0p78Tm5q5f3AkKI2fhAjlOUTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}