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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e666bdefa88b078e3d8854ac9f63bcf0701c67bdee3fffc7720308622859cc' 
  AND token = '395AWv5R5Czj1wHKkPu1KlyJ6wTf41chdSxag4qUmbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}