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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26f627ebcbfa17286e437912f0e2f2f4e1e7884c72e1f495ddf53578ba011ae6' 
  AND token = 'd+eOQpPr0BHvsGLl/mqZOC7bPvV2wOMEk4kTdWHwyzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}