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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c2d8f7c5b7fa1b330895f5e75a0bc9de25b718237773e5497a735e03537a24c' 
  AND token = '2KW0HywnSq7oEWRzQbtmDSwcHLY4NQYRNt1g4hH8BYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}