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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abf1109ae3237404b77464862126be50cfec0da0285b8d2c2d5edbfa65fea72b' 
  AND token = 'ngt7Zj9rzClrUN7cF+5UpohrdcKazzQ+cY4q3eSFmLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}