SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85105093537db305d8cdf9cbd22f2ef4e6d7fd46b35470832ea3b61f0aa2a3e2' 
  AND token = 'VtI0K9iTIx0IEHHbL74pZ+u3NRF/f2Af1XWTFasnH4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}