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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ca1b4167fabecd2fa49cf243498c66dff75e5787984beb645dfcdb32f02581' 
  AND token = 'y+4bIYAD9xk8gyjlMXQePHa37f3cb/qjgn3B4S3pvdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}