SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c576a8a48e92aa8ab34f92605a2853fca4cc73f3e70e14319be717dcf313b5' 
  AND token = 'Ap3hx2BMmmlIBUgc45SGCigduQ7AknSf9o1sSeD44cU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}