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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edff3770bf725f33eef82028aca184cdca9dc5fdb6b80af771ce39fcb47bc7b4' 
  AND token = 'zqMRYJGxtCoAtrmR2m2pQ8sqy7D+o5zKnU9jiuFnCNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}