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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b667a4da611fcc933b0ff0fa5df9efae483efb88e367f64698c66346a0d2199' 
  AND token = 'R3mmd/7rJe63HQRKlDPVYJ1oOtm7B3A0G9qs8nRWjmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}